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Human Chorionic Gonadotropin (abbreviated hCG) is formed exclusively in the placenta of a pregnant woman, being a natural hormone. It is produced in the laboratory from the urine of a woman during pregnancy. Its effect on humans is similar to that of luteinizing hormone, the forerunner of testosterone.

Oral hCG is not effective. This has been proven through numerous studies. Experiments conducted in the United States of America proved that human chorionic gonadotropin with nutritional supplements do not give any result.

Pharmacology

Pharmacokinetics

It is produced in the form of injections for administration subcutaneously or intramuscularly. This drug is first diluted with a special liquid attached to it, inside the ampoule. It is injected into the muscles. The substance is very quickly absorbed, and is valid for at least five to six days.

Pharmacodynamics

The effect of hCG on human body is similar to the luteinizing hormone. It also signals, going through the pituitary, about the active stimulation of testosterone. hCG in the form of drug, in addition to increasing the production of testosterone, enhances the qualitative properties of sperm, making the secondary sexual characteristics in both women and men much more pronounced. In females chorionic gonadotropin enhances progesterone synthesis, significantly increases the rate of egg maturation. In addition, this drug helps to form the placenta.

The amount of hCG produced allows you to regulate the feedback in the chain of interaction between the hypothalamus-pituitary-testes axis. A lack of human chorionic gonadotropin provokes a decrease in size and functionality of the testicles. Increasing the concentration of this human hormone allows the artificial introduction of both synthetic testosterone and its various analogues, which allows the hypogalamic-pituitary-gonadal system to make it clear that there is no need to synthesize gonadotropin and gonadoliberin. This causes the testes to lose their functions, which become much smaller.

Usage and Dosage

Bodybuilding

The use of gonadotropin is recommended for athletes who take testosterone and its analogues. This helps to avoid testicular atrophy, which is considered the main function of this drug. Bodybuilders who do not have much experience, use hCG in combination cycles for the growth of muscle mass. Due to the fact that this drug increases the level of testosterone synthesis, it is taken. It is used, including in the period of cutting, in order to maintain muscle mass against the background of reduced caloric intake.

Chorionic gonadotropin, as studies have shown, is ineffective for the reception with an anabolic goal in bodybuilding. This is due to the fact that it can provoke numerous problems. Stimulation of the synthesis of testosterone provided by this drug is much less than in other synthetic forms of this hormone, and the side effects are much higher. Therefore, many are wondering about why, then why take HCG. His main advantage, which receives a bodybuilder, taking it, is to prevent testicular atrophy.

The use of gonadotropin for prophylactic purposes to prevent the reduction of testicles requires small dosages. Therefore, taking this drug for this purpose minimizes the risks that are obtained when it exhibits anabolic properties. The main advantage of hCG on cycle of anabolic steroids is that it can significantly reduce the negative effects of many of these drugs. Its use is allowed during the cutting period in order to preserve muscle mass. If HCG is administered for a long time, it allows you to maintain the axis of the hypothalamus-pituitary-testicular functioning. It is not recommended to take this drug on post-cycle therapy.

Cycle

Short Cycles

When anabolic steroids are taken for no longer than five or six weeks, then there is no need for hCG injections.

Long Cycles

Large dosages or use of anabolic steroids for a long time requires the introduction of 250 to 500 IU of human chorionic gonadotropin twice a week. When hCG is not used in a heavy cycle, it is taken during post-cycle therapy, which requires a dosage of 2.000 IU. This drug is administered three weeks every other day.

Endless Cycles

Professional bodybuilders use anabolic steroids almost always. This means that taking chorionic gonadotropin is required regularly. Every five weeks, with a break of seven to fourteen days is required.

Side Effects

The use of hCG can lead to the following side effects:

• suppress the production of gonadotropin-releasing hormone;
• provoke dysfunction of the hypothalamus-pituitary-testes chain;
• lead to gynecomastia and masculinization;
• cause acne;
• cause afforestation and increase body hairiness;
• enlarge the prostate in size.

Reviews

The use of gonadotropin in post-cycle therapy, as well as in short and long-term cycles with anabolic steroids, as a rule, has received a large number of positive reviews. Use of hCG is advisable only for men. This drug is not taken by women, including as a means to eliminate the effects of aromatization.

There are practically no negative reviews about chorionic gonadotropin. This is due to the fact that it is rarely taken for anabolic purposes. Negative reviews are most often associated with the fact that some athletes try to gain ten kilograms of muscle for a cycle without muscle loss.

References

1. A Detailed Look At hCG
2. hCG – The Natural Hormone To Help Produce Testosterone
3. hCG (Human Chorionic Gonadotropin)

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